The most startup-friendly digital health lab, connecting entrepreneurs to experts, institutions and resources with no equity taken.

When entrepreneurs win, patients win.

  • Digital Healthcare Lab: Connecting entrepreneurs with world-class strategic partners in healthcare
  • Community Access: Join the world's preeminent digital health community
  • Office Space: Free offices in the heart of Boston's healthcare ecosystem
  • Health Challenges: Resources driven to specific, top opportunities in digital health
  • Champions & Advisors: Mutual matchmaking with corporate & institutional Champions, mentors & advocates ready to help startups achieve success.
  • Awards: $250,000 in awards, no equity taken.
  • Questions? Write us at pulsehelp@masschallenge.org

Meet the PULSE@ startups:

This community will better healthcare

We believe that when entrepreneurs and the ecosystem come together to solve problems we will accelerate innovation and transform healthcare.

In partnership with the Commonwealth of Massachusetts, MeHI, MACP, and the region's leading institutions, corporations, payors and healthcare experts, PULSE@ brings a startup-friendly approach to accelerating the development of new digital health innovations.

Startup-friendly digital health lab

A startup-friendly approach provides entrepreneurs access to resources critical for growth.


Through mutual-matchmaking, every PULSE@ startup connects with a Champion (institution, corporation, payor) to help the startup reach critical milestones:

  • Key advisor introductions
  • Co-development
  • Product & clinical validation
  • Customer connections
  • Strategic investments


Experts from the Massachusetts digital health and innovation ecosystem volunteer time and expertise to support participating entrepreneurs.

Office Space

Startups gain access to 8,000 sq ft of free office space in The Fenway, a growing innovation center in Boston and a stone's throw from the Longwood Medical Area.

Community Access

PULSE@ entrepreneurs get plugged into the Massachusetts digital healthcare ecosystem.


MassChallenge and partners will award up to $250,000 in no-equity scholarships and prizes at beginning and conclusion of the program.

Connect with partners ready to work

Health Challenges bring the community and resources together to help entrepreneurs address the greatest opportunities in digital health. PULSE@ is seeking startups that address the following:

Access and Referral Management | Aging | Behavioral or Psychiatric Condition Support | Biosensors | Care Coordination | Caregiving | Chronic Disease Management | Clinical Trial Recruitment | Clinician Collaboration and Communication | Concierge Medicine | Connected Devices | Cybersecurity | Data Analytics & Big Data | Data to Understand Disease Progression | Global Sexual Health | Holistic Health | Home Health Care | Improving the Patient-Provider Experience | Interoperability | Neurological Solutions | New Care Delivery Models (virtual care, econsults, etc) | Nutrition | Oncology | Opioid Abuse Support and Prevention | Patient Education and Self-Management | Patient Engagement | Patient Monitoring | Patient Personalization | Patient Transportation | Rare Diseases | Readmission Prevention | Reduce Administrative Burden | Remote Clinical Trial Management | Scheduling and Slot-Utilization | Social Media | Specialty Pharmacy | Telehealth | Wearables | Wellness | Women's Health | AND the Best in Digital Health

Learn why our champions care about digital health and startups:

PULSE@ Partners

Pulse@ Partners

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